paired-like homeobox 2a, Mouse, Polyclonal Antibody, Abnova
Mouse polyclonal antibody raised against a full-length human PHOX2A protein.
Manufacturer: Abnova Corporation H00000401B01
The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeqSequence: MDYSYLNSYDSCVAAMEASAYGDFGACSQPGGFQYSPLRPAFPAAGPPCPALGSSNCALGALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAGAAGAKKGEARCSSEDDDSKESTCSPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGPQPLKGALWAGVAGGGGGGPGAGAAELLKAWQPAESGPGPFSGVLSSFHRKPGPALKTNLF
|paired-like homeobox 2a|
|Immunofluorescence, Western Blot|
|Mouse polyclonal antibody raised against a full-length human PHOX2A protein.|
|PHOX2A (NP_005160.2, 1 a.a. ~ 284 a.a) full-length human protein.|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
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