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paired-like homeobox 2a, Mouse, Polyclonal Antibody, Abnova™

Mouse polyclonal antibody raised against a full-length human PHOX2A protein.

Manufacturer:  Abnova Corporation H00000401B01

Catalog No. 89-004-935


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Description

Description

The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq

Sequence: MDYSYLNSYDSCVAAMEASAYGDFGACSQPGGFQYSPLRPAFPAAGPPCPALGSSNCALGALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAGAAGAKKGEARCSSEDDDSKESTCSPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGPQPLKGALWAGVAGGGGGGPGAGAAELLKAWQPAESGPGPFSGVLSSFHRKPGPALKTNLF
Specifications

Specifications

paired-like homeobox 2a
Unconjugated
No additive
NM_005169.2
ARIX|CFEOM2|FEOM2|MGC52227|NCAM2|PMX2A
Mouse
50 uL
Transcription Regulation
Y
Polyclonal
Human
Immunofluorescence, Western Blot
Mouse polyclonal antibody raised against a full-length human PHOX2A protein.
PHOX2A
Serum
PHOX2A
PHOX2A (NP_005160.2, 1 a.a. ~ 284 a.a) full-length human protein.
RUO
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Primary
401
Documents
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