PIK3CG Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA528070
PA5-28070 targets PI3 kinase p110 gamma in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-28070 immunogen is synthetic peptide corresponding to a region within amino acids 1041 and 1102 of Human PI3 kinase p110 gamma. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.PIK3CG belongs to the pi3/pi4-kinase family of proteins. It is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintece of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene for this protein is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias.
|Synthetic peptide corresponding to a region within amino acids 1041 and 1102 of Human PI3 kinase p110 gamma|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 40% glycerol and 0.01% thimerosal; pH 7|
|PI3CG, PI3K, PI3Kgamma, PIK3, 1-phosphatidylinositol 3-kinase, PI3-kinase subunit gamma, PI3K-gamma, p110-gamma, p110gamma, p120-PI3K, phosphatidylinositol 3 kinase gamma, p110 gamma, phosphatidylinositol 3-kinase catalytic 110-kD gamma, phosphatidylinositol 3-kinase, catalytic, gamma polypep|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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