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PIASy Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA511346

Catalog No. PIPA511346

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

PIASy1 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. This protein plays a crucial role in transcriptional coregulation of various cellular pathways, including the STAT pathway, the p53 pathway, the wnt pathway and the steroid hormone signaling pathway. PIASy1 is involved in gene silencing, and promotes PARK7 sumoylation.
Specifications

Specifications

PIASy
Polyclonal
PBS with 0.09% sodium azide
Q8N2W9
E3 SUMO-protein ligase PIAS4; Protein inhibitor of activated STAT protein 4; Protein inhibitor of activated STAT protein gamma; PIAS-gamma; PIASy; PIAS4; PIASG
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
51588
Immunohistochemistry, Western Blot
Unconjugated
PIAS4
Liquid
PIAS4
KLH conjugated synthetic peptide between 48-79 amino acids from the N-terminal region of human PIASy
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
Antibody
Polyclonal
Human
Documents
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