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PIH1D1 Mouse anti-Human, Clone: 4F5-1E10, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA522090

Catalog No. PIMA522090


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Description

Description

Peptide Sequence: MANPKLLGLE LSEAEAIGAD SARFEELLLQ ASKELQQAQT TRPESTQIQP QPGFCIKTNS SEGKVFINIC HSPSIPPPAD VTEEELLQML EEDQAGFRIP MSLGEPHAEL DAKGQGCTAY DVAVNSDFYR RMQNSDFLRE LVITIAREGL EDKYNLQLNP EWRMMKNRPF MGSISQQNIR SEQRPRIQEL GDLYTPAPGR AESGPEKPHL NLWLEAPDLL LAEIDLPKLD GALGLSLEIG ENRLVMGGPQ QLYHLDAYIP LQINSHESKA AFHRKRKQLM VAMPLLLVPS

Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (PubMed:17636026). Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription (PubMed:22368283, PubMed:24036451). Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 (PubMed:20864032). Positively regulates the assembly and activity of the mTORC1 complex (PubMed:24036451).
Specifications

Specifications

PIH1D1
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.4
Q9NWS0
PIH1D1
PIH1D1 (AAH01108, 1 a.a. ∽ 290 a.a) full-length recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
4F5-1E10
Unconjugated
PIH1D1
Liquid
Mouse
IgG1, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
55011
Documents
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