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PIN Mouse, Unlabeled, Clone: 4, BD

Mouse Monoclonal Antibody

$213.00

Specifications

Antigen PIN
Isotype IgG1
Immunogen Rat PIN aa. 1-89
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
BDB610726
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BD Biosciences
610726
50μg
Each for $213.00
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BDB610727
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BD Biosciences
610727
150μg This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
Description

Description

PIN (protein inhibitor of nNOS) is a small protein of 89 amino acids initially described as a light chain subunit of dynein and as an inhibitor of the neuronal nitric oxide synthase isoform (nNOS). In vitro, PIN has been reported to bind to a unique nNOS domain encompassing amino acids 163-245. PIN inhibits nNOS activity and blocks the formation of the active nNOS dimer. Although ubiquitously expressed, PIN levels are reportedly highest in brain and testis. Immunolocalization studies in Drosophila melanogaster detected a cytoplasmic distribution of PIN. Partial-loss-of-function of PIN resulted in morphologic and developmental changes in the bristles, wings, and female sterility of D. melanogaster. Deletion of PIN resulted in lethality with the characteristic morphology of apoptotic cells.

Immunofluorescence, Immunoprecipitation, Western Blotting

Specifications

Specifications

PIN
Rat PIN aa. 1-89
Unconjugated
Cell Biology
Mouse
Affinity Purified
Monoclonal
Protein Inhibitor of nNOS
IgG1
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Immunofluorescence, Western Blot
RUO
4
250μg/mL
Store undiluted at -20°C.
SDS
Product Certifications

For Research Use Only.

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