Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

PIR-A/PIR-B Rat anti-Mouse, Clone: 404127, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA524140

Catalog No. PIMA524140


Add to cart

Description

Description

Reconstitute at 0.5 mg/mL in sterile PBS.

Paired Ig-like receptors of activating (PIR)-A and -B are expressed on B lymphocytes, macrophages, dendritic cells, platelets, granulocytes, and mast cells, but not on T cells, NK cells, and erythrocytes. These cell surface glycoproteins contain six extracellular Ig-like domains with distinct cytoplasmic and transmembrane regions. The PIR-A receptor activates through signaling molecules containing immunoreceptor tyrosine-based activation motifs. In contrast, the PIR-B receptor inhibits through proteins possessing immunoreceptor tyrosine-based inhibitory motifs. PIRs bind MHC class I to modulate immune system homeostasis and cell signaling.
Specifications

Specifications

PIR-A/PIR-B
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P97484
pirb, Leukocyte immunoglobulin-like receptor subfamily B member 3, LIR-3, Leukocyte immunoglobulin-like receptor 3, Cell-surface glycoprotein p91, Paired immunoglobulin-like receptor B, PIR-B, Lilrb3, Pirb, Leukocyte immunoglobulin-like receptor subfamily B member 4, Mast cell surface glycoprotein Gp49B, CD85k, Lilrb4, Gp49b, Pira1
Rat
IgG2A
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
18722, 18733
Flow Cytometry
404127
Unconjugated
Pirb
Lyophilized
PIRA1, PIRB
Mouse myeloma cell line NS0-derived recombit mouse PIR-A1 Gly24-Met650
Protein A/G
RUO
Antibody
Monoclonal
Mouse
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit