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PIT1 Rabbit anti-Canine, Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA124436

Catalog No. PIPA124436


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Description

Description

PA1-24436 detects PIT1/POU1F1 in human, mouse, rat, and canine samples. PA1-24436 has been successfully used in Western blot and immunohistochemistry (paraffin) procedures. The PA1-24436 immunogen is a synthetic peptide region of human POU1F1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans . PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP.
Specifications

Specifications

PIT1
Polyclonal
Unconjugated
POU1F1
Liquid
POU1F1
Synthetic peptide region of human POU1F1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Canine, Human, Mouse, Rat
Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 2% sucrose and 0.09% sodium azide
Q9TTI7, P28069, Q00286, P10037
POU1F1
Rabbit
IgG
50 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
18736, 25517, 403753, 5449
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