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PKA alpha/beta Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA513737

Catalog No. PIPA513737

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by the PRKACA gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase.
Specifications

Specifications

PKA alpha/beta
Polyclonal
Unconjugated
PRKACB
Liquid
PRKACA, PRKACB
KLH conjugated synthetic peptide between 9-40 amino acids from the N-terminal region of human PKA C-alpha/PKA C-beta
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
1.1 mg/mL
PBS with 0.09% sodium azide
P17612, P22694, P05132, P68181
cAMP-dependent protein kinase, alpha-catalytic subunit, PRKACA, PKACA, PKACB, PRKACB
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
18747, 18749, 5566, 5567
Documents
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