PKA beta Mouse anti-Human, Clone: 2G8-1D12, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA519698
Peptide Sequence: MGNAATAKKG SEVESVKEFL AKAKEDFLKK WENPTQNNAG LEDFERKKTL GTGSFGRVML VKHKATEQYY AMKILDKQKV VKLKQIEHTL NEKRILQAVN FPFLVRLEYA FKDNSNLYMV MEYVPGGEMF SHLRRIGRFS EPHARFYAAQ IVLTFEYLHS LDLIYRDLKP ENLLIDHQGY IQVTDFGFAK RVKGRTWTLC GTPEYLAPEI ILSKGYNKAV DWWALGVLIY EMAAGYPPFF ADQPIQIYEK IVSGKNFcAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Three alternatively spliced transcript variants encoding distinct isoforms have been observed.
|PBS with no preservative; pH 7.4|
|PRKC Pan, Protein kinase C alpha type, PKC-A, PKC-alpha, PRKCA, PKCA, PRKACA, PKCB, PRKCB1, Protein kinase C beta type, PKC-B, PKC-beta|
|-20° C, Avoid Freeze/Thaw Cycles|
|PRKACB (AAH16285, 1 a.a. ∽ 257 a.a) full-length recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
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