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PKA beta Mouse anti-Human, Clone: 2G8-1D12, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA519698

Catalog No. PIMA519698


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Description

Description

Peptide Sequence: MGNAATAKKG SEVESVKEFL AKAKEDFLKK WENPTQNNAG LEDFERKKTL GTGSFGRVML VKHKATEQYY AMKILDKQKV VKLKQIEHTL NEKRILQAVN FPFLVRLEYA FKDNSNLYMV MEYVPGGEMF SHLRRIGRFS EPHARFYAAQ IVLTFEYLHS LDLIYRDLKP ENLLIDHQGY IQVTDFGFAK RVKGRTWTLC GTPEYLAPEI ILSKGYNKAV DWWALGVLIY EMAAGYPPFF ADQPIQIYEK IVSGKNF

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Three alternatively spliced transcript variants encoding distinct isoforms have been observed.
Specifications

Specifications

PKA beta
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
P22694
PRKC Pan, Protein kinase C alpha type, PKC-A, PKC-alpha, PRKCA, PKCA, PRKACA, PKCB, PRKCB1, Protein kinase C beta type, PKC-B, PKC-beta
Mouse
IgG1, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
5567
ELISA
2G8-1D12
Unconjugated
PRKACB
Liquid
PRKACB
PRKACB (AAH16285, 1 a.a. ∽ 257 a.a) full-length recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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