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PKC alpha Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA513739

Catalog No. PIPA513739

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PKC alpha is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
Specifications

Specifications

PKC alpha
Polyclonal
Unconjugated
PRKCA
Liquid
PRKCA
KLH conjugated synthetic peptide between 299-329 amino acids from the C-terminal region of human PKC alpha
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
Antibody
Polyclonal
Human
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1.38 mg/mL
PBS with 0.09% sodium azide
P17252
Protein kinase C, alpha type; PRKCA; PKCA; PRKACA
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
5578
Documents
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