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PKC epsilon Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA513745

Catalog No. PIPA513745


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Description

Description

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PKC epsilon is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior.
Specifications

Specifications

PKC epsilon
Polyclonal
PBS with 0.09% sodium azide
Q02156
Protein kinase C, epsilon type; nPKC-epsilon; PRKCE; PKCE
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
5581
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
PRKCE
Liquid
PRKCE
KLH conjugated synthetic peptide between 206-236 amino acids from the N-terminal region of human PKC epsilon
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
Antibody
Polyclonal
Human
Documents
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