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PKN3 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA515127

Catalog No. PIPA515127

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

PKN3, a protein kinase C-related molecule, mediates maligt cell growth downstream of activated PI3K. PKN3 is required for invasive prostate cell growth as assessed by 3D cell culture assays and in an orthotopic mouse tumor model by inducible expression of short hairpin RNA (shRNA). PKN3 is regulated by PI3K at both the expression level and the catalytic activity level. Therefore, PKN3 might represent a preferred target for therapeutic intervention in cancers that lack tumor suppressor PTEN function or depend on chronic activation of PI3K.
Specifications

Specifications

PKN3
Polyclonal
PBS with 0.09% sodium azide
Q6P5Z2
Serine/threonine-protein kinase N3; Protein kinase PKN-beta; Protein-kinase C-related kinase 3; PKNBETA; PKN3
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
29941
Immunohistochemistry, Western Blot
Unconjugated
PKN3
Liquid
PKN3
KLH conjugated synthetic peptide between 463-492 amino acids from the C-terminal region of human PKN beta
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
Antibody
Polyclonal
Human
Documents
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