PAPPA2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA521046
A suggested positive control is Hela cell lysate. PA5-21046 can be used with blocking peptide PEP-1160.PLAC3 (placenta-specific protein 3), also known as PAPP-A2, is a metalloproteinase that cleaves the insulin-like growth factor-binding protein (IGFBP)-5 in a IGF-independent fashion. It has been suggested that the cleavage of IGFBP-5 and to a lesser extent IGFBP-3 produced in the maternal decidua promotes feto-placental growth. Recent studies have shown elevated levels of PLAC3 in hypertensive disorders of pregcy including preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome.
|A 15 amino acid peptide near the amino terminus of human PLAC3.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 0.02% sodium azide|
|RP4-774I24.1, PAPP-A2, PAPPE, PLAC3; PAPP-E; pappalysin-2; placenta-specific 3; pregcy-associated plasma preproprotein-A2; pregcy-associated plasma protein E1|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|23850, 60676, 680415|
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