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PAPPA2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA521046

Catalog No. PIPA521046


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Description

Description

A suggested positive control is Hela cell lysate. PA5-21046 can be used with blocking peptide PEP-1160.

PLAC3 (placenta-specific protein 3), also known as PAPP-A2, is a metalloproteinase that cleaves the insulin-like growth factor-binding protein (IGFBP)-5 in a IGF-independent fashion. It has been suggested that the cleavage of IGFBP-5 and to a lesser extent IGFBP-3 produced in the maternal decidua promotes feto-placental growth. Recent studies have shown elevated levels of PLAC3 in hypertensive disorders of pregcy including preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome.
Specifications

Specifications

PAPPA2
Polyclonal
Unconjugated
PAPPA2
Liquid
PAPPA2
A 15 amino acid peptide near the amino terminus of human PLAC3.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9BXP8
RP4-774I24.1, PAPP-A2, PAPPE, PLAC3; PAPP-E; pappalysin-2; placenta-specific 3; pregcy-associated plasma preproprotein-A2; pregcy-associated plasma protein E1
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
23850, 60676, 680415
Documents
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