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Plasminogen Goat anti-Human, Biotin, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA126883

Catalog No. PIPA126883


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Description

Description

PA1-26883 detects Plasminogen from human samples. PA1-26883 has been successfully used in ELISA and Western blot procedures. The PA1-26883 immunogen is Plasminogen from human plasma. Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20° C or below, avoiding multiple freeze-thaw cycles.

Plasminogen is a plasma protein synthesised mostly in the liver. Plasma concentration is usually in the range of 70 - 200mg/L. Plasminogen is activated by tissue-plasminogen activator, urokinase and streptokinase, to form plasmin. Activation results from the cleavage and release of the preactivation peptide. Angiostatin, an internal fragment of plasminogen, is a potent inhibitor of angiogenesis, which selectively inhibits endothelial cell proliferation. Angiostatin potently inhibits tumor growth and can maintain metastatic and primary tumors in a dormant state. It is defined by a balance of proliferation and apoptosis of the tumor cells and is composed of plasminogen first four cringle structures. This molecule is generated by proteolytic cleavage of plasminogen.
Specifications

Specifications

Plasminogen
Polyclonal
Biotin
PLG
Liquid
Goat
IgG
1 mg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
5340
ELISA, Western Blot
10 mg/mL
0.02M potassium phosphate with 0.15M NaCl, 10mg/mL BSA and 0.01% sodium azide; pH 7.2
P00747
PLG
Plasminogen from human plasma.
IgG fraction
RUO
Antibody
Polyclonal
Human
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