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PLD2 Rabbit anti-Human, Non-human primate, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523335

Catalog No. PIPA523335


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Description

Description

PLD2 is a peripheral membrane protein belonging to phospholipase D family with a PH domain, two PLD phosphodiesterase domains and a PX (phox homology) domain that plays a regulatory rather than catalytic role. PLD2 catalyzes the hydrolysis of phosphatidylcholine (PC) to produce phosphatidic acid and choline. PLD2 may function in regulated secretion, signal-induced cytoskeletal regulation and/or endocytosis, transcriptional regulation, and cell cycle control. It is usually stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and activated by the ADP-ribosylation factor-1 (ARF-1). PLD2 is activated by agonist stimulation of both tyrosine kinase and G protein-coupled receptors and is also known to interact with EGFR and PIP5K1A. PLD2, localized to plasma membrane caveolae, is ubiquitously expressed in most tissues.
Specifications

Specifications

PLD2
Polyclonal
whole serum with 50% glycerol and 0.025% sodium azide
O14939
PLD1C, choline phosphatase 2, hPLD2, phosphatidylcholine-hydrolyzing phospholipase D2
Rabbit
IgG
RUO
Antibody
Polyclonal
Human, Non-human Primate
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
PLD2
Liquid
PLD2
Amino acids 199-216 DLGRKGLEGMIRKRSGGH of human PLD2 protein were used as the immunogen.
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
5338
Documents
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