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Pleckstrin Mouse, Unlabeled, Clone: 25, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 610503

Catalog No. BDB610503


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Description

Description

Pleckstrin was identified in platelets as a major substrate for Protein Kinase C. Both ends of the molecule are the prototypes of a widely distributed module named the “pleckstrin homology” (PH) domain that consists of seven β-strands. In pleckstrin, the PH domains are separated by 150 amino acids. PH domains are commonly found in signal transduction proteins. Although pleckstrin's role is still poorly defined, PH domains are widely used by receptors for interaction with G proteins and for membrane attachment. It is thought that PH domains regulate the binding of pleckstrin to membranes and modulate phosphoinositide metabolism by its binding to G proteins.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Specifications

Specifications

Pleckstrin
25
Unconjugated
Affinity Purified
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
50μg
Cell Biology
Primary
Human, Murine
Western Blot
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Murine
IgG1
RUO
Store undiluted at -20°C.
Monoclonal
Documents
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