PLXDC2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520466
A suggested positive control is human brain tissue lysate. PA5-20466 can be used with blocking peptide PEP-0583.Plxdc2, also known as Tumor endothelial marker 7-related (TEM7R) encodes a protein with 57% amino acid identity to TEM7, the most abundant tumor endothelial marker. Plxdc2 is strongly expressed in the endothelial cells of the tumor stroma, but not in the endothelial cells of normal colonic tissue. Plxdc2 is also expressed at high levels in vessels of some normal tissues, with highest expression in muscle and lung. Plxdc2 and TEM7 may be important for tumor angiogenesis in humans. Cortactin was identified as a protein capable of binding to the extracellular region of both TEM7 and Plxdc2, and may provide new opportunities for the delivery of therapeutic and imaging agents to the vessels of solid tumors.
|An 18 amino acid peptide from near the amino terminus of human Plxdc2.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|UNQ2514/PRO6003, TEM7R; 1200007L24Rik; plexin domain-containing protein 2; tumor endothelial marker 7-related protein|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|361282, 67448, 84898|
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