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PLXDC2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520466

Catalog No. PIPA520466


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Description

Description

A suggested positive control is human brain tissue lysate. PA5-20466 can be used with blocking peptide PEP-0583.

Plxdc2, also known as Tumor endothelial marker 7-related (TEM7R) encodes a protein with 57% amino acid identity to TEM7, the most abundant tumor endothelial marker. Plxdc2 is strongly expressed in the endothelial cells of the tumor stroma, but not in the endothelial cells of normal colonic tissue. Plxdc2 is also expressed at high levels in vessels of some normal tissues, with highest expression in muscle and lung. Plxdc2 and TEM7 may be important for tumor angiogenesis in humans. Cortactin was identified as a protein capable of binding to the extracellular region of both TEM7 and Plxdc2, and may provide new opportunities for the delivery of therapeutic and imaging agents to the vessels of solid tumors.
Specifications

Specifications

Plxdc2
Polyclonal
Unconjugated
PLXDC2
Liquid
PLXDC2
An 18 amino acid peptide from near the amino terminus of human Plxdc2.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q6UX71, Q9DC11
UNQ2514/PRO6003, TEM7R; 1200007L24Rik; plexin domain-containing protein 2; tumor endothelial marker 7-related protein
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
361282, 67448, 84898
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