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PML Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA512185

Catalog No. PIPA512185


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Description

Description

PML is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL).
Specifications

Specifications

PML
Polyclonal
PBS with 0.09% sodium azide
P29590
Tripartite motif-containing protein 19; RING finger protein 71; MYL; RNF71; TRIM19
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
5371
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
PML
Liquid
PML
KLH conjugated synthetic peptide between 470-499 amino acids from human PML Sumoylation Site
Antigen Affinity Chromatography, Protein A
RUO
Antibody
Polyclonal
Human
Documents
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