PMP22 Rabbit anti-Human, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA138475
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is pancreas tissue.PMP-22 (Peripheral Myelin Protein) is a glycoprotein expressed in the compact myolin of the peripheral nervous system. In the peripheral nervous system, PMP-22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) and protein P0 during nerve development and regeneration. Alterations in the level of this protein cause several genetic human diseases. If the protein is duplicated, patients develop Charcot-Marie-Tooth disease. If one copy of the gene is deleted, they suffer from the inherited tendency to pressure palsies.
|PBS with 1% BSA and <0.1% sodium azide; pH 7.6|
|CMT1A, CMT1E, DSS, GAS-3, HMSNIA, HNPP, Sp110, PMP-22, growth arrest-specific 3, growth arrest-specific protein 3|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)|
|Synthetic peptide from near C-terminus of human PMP-22.|
|Antigen affinity chromatography|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok