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Cytochrome P450 Reductase, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA129792

Catalog No. PIPA129792


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Description

Description

PA1-29792 detects POR from mouse, monkey, human, rat, canine, guinea pig, hamster, porcine, rabbit and sheep samples. PA1-29792 has been successfully used in Western blot applications. Suggested positive controls for this product are rat liver, NADPH, cytochrome, P450 and reductase protein. The PA1-29792 immunogen is purified rat liver NADPH-Cytochrome P450 reductase.

This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
Specifications

Specifications

Cytochrome P450 Reductase
Polyclonal
PBS with 50% glycerol and 0.09% sodium azide
P37039, P16435, P37040, P04175, P00389, P00388
CPR, CYPOR, DKFZp686G04235, FLJ26468, P450R
Rabbit
IgG
50 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
100135602, 100170114, 100301554, 100689241, 101115252, 18984, 29441, 489816, 5447
Western Blot
Unconjugated
POR
Liquid
POR
Purified rat liver NADPH-Cytochrome P450 reductase.
Protein A
RUO
Antibody
Polyclonal
Canine, Guinea Pig, Hamster, Human, Mouse, Non-human primate, Ovine, Porcine, Rabbit, Rat
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