POT1 Rabbit anti-Human, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA141147
Suggested positive control: HL-60, antigen standard for POT1 (transient overexpression lysate).POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintece. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
|Synthetic peptide corresponding to residues 450-500 of human POT1.|
|Gel Shift, Western Blot|
|PBS with 0.05% BSA and 0.05% sodium azide|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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