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POT1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA141147

Catalog No. 01-675-724


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Description

Description

Suggested positive control: HL-60, antigen standard for POT1 (transient overexpression lysate).

POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintece. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
Specifications

Specifications

POT1
Polyclonal
Unconjugated
POT1
Liquid
POT1
Synthetic peptide corresponding to residues 450-500 of human POT1.
Protein G
RUO
Antibody
Polyclonal
Human
Gel Shift, Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Q9NUX5
DKFZp586D211, HPOT1
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
25913
Documents
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