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PPP2R4 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA528296

Catalog No. PIPA528296


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Description

Description

PA5-28296 targets PPP2R4 in WB applications and shows reactivity with Human and mouse samples. The PA5-28296 immunogen is recombit fragment corresponding to a region within amino acids 60 and 316 of Human PPP2R4. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B ft./PR61, and B ft. ft./PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B ft. family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
Specifications

Specifications

PPP2R4
Polyclonal
Unconjugated
PTPA
Liquid
PTPA
Recombit fragment corresponding to a region within amino acids 60 and 316 of Human PPP2R4
Protein A
RUO
Antibody
Polyclonal
Human, Mouse
Western Blot
6.31 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Q15257, P58389
PP2A, PR53, PTPA, PP2A phosphatase activator, PP2A subunit B′ isoform PR53, phosphotyrosyl phosphatase activator, protein phosphatase 2A, regulatory subunit B′ (PR 53), serine/threonine-protein phosphatase 2A activator, serine/threonine-protein phosphatase 2A regulatory subunit
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
110854, 5524
Documents
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