PPP2R4 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA528296
PA5-28296 targets PPP2R4 in WB applications and shows reactivity with Human and mouse samples. The PA5-28296 immunogen is recombit fragment corresponding to a region within amino acids 60 and 316 of Human PPP2R4. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B ft./PR61, and B ft. ft./PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B ft. family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
|Recombit fragment corresponding to a region within amino acids 60 and 316 of Human PPP2R4|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|PP2A, PR53, PTPA, PP2A phosphatase activator, PP2A subunit B′ isoform PR53, phosphotyrosyl phosphatase activator, protein phosphatase 2A, regulatory subunit B′ (PR 53), serine/threonine-protein phosphatase 2A activator, serine/threonine-protein phosphatase 2A regulatory subunit|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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