PRAME Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523157
DescriptionPRAME is a 509 amino acid protein belonging to the PRAME family consisting of 7 LRR (leucine-rich) repeats. It is a tumor antigen expressed in human melanomas and is recognized by cytolytic T lymphocytes. It ft.s overexpression frequently observed in human cancers confers growth or survival advantages by antagonizing retinoic acid receptor (RAR) signaling. PRAME serves as a candidate marker for monitoring childhood acute leukemia. It is expressed in testis and acute leukemias.
|whole serum with 50% glycerol and 0.025% sodium azide|
|CT130, MAPE, OIP4, OIP-4, Opa-interacting protein OIP4, cancer/testis antigen 130, melanoma antigen preferentially expressed in tumors, opa-interacting protein 4, preferentially expressed antigen of melanoma|
|Synthetic peptide (492 CGDRTFYDPEPIL 502) of PRAME protein.|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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