protein kinase, AMP-activated, beta 2 noncatalytic subunit (B01), Mouse anti-Human, Polyclonal Antibody, Abnova
Mouse polyclonal antibody raised against a full-length human PRKAB2 protein.
Manufacturer: Abnova Corporation H00005565B01
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and noncatalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. [provided by RefSeqSequence: MGNTTSDRVSGERHGAKAARSEGAGGHAPGKEHKIMVGSTDDPSVFSLPDSKLPGDKEFVSWQQDLEDSVKPTQQARPTVIRWSEGGKEVFISGSFNNWSTKIPLIKSHNDFVAILDLPEGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSDFEVFDALKLDSMESSETSCRDLSSSPPGPYGQEMYAFRSEERFKSPPILPPHLLQVILNKDTNISCDPALLPEPNHVMLNHLYALSIKDSVMVLSATHRYKKKYVTTLLYKPI
|protein kinase, AMP-activated, beta 2 non-catalytic subunit|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Mouse polyclonal antibody raised against a full-length human PRKAB2 protein.|
|PRKAB2 (NP_005390, 1 a.a. ~ 272 a.a) full-length human protein.|
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