PRKAR2A Mouse anti-Bovine, Human, Porcine, Clone: RS30, Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA120070

Catalog No. PIMA120070

Description

MA1-20071 detects PRKAR2 in human, bovine and porcine samples. MA1-20071 has been successfully used in ELISA and immunofluorescence procedures. The MA1-20071 immunogen is purified regulatory subunit of cAMP-dependent protein kinase type II from bovine b

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of AMPK.

Specifications

• Antigen: PRKAR2A
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene Accession No.: P00515, P13861, P05207
• Gene Symbols: PRKAR2A
• Immunogen: Purified regulatory subunit of cAMP-dependent protein kinase type II from bovine brain.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Bovine, Human, Porcine
• Product Type: Antibody
• Isotype: IgG2a

• Applications: ELISA, Immunocytochemistry, Immunofluorescence
• Clone: RS30
• Gene: PRKAR2A
• Gene Alias: MGC3606, PKR2, PRKAR2
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 100139910, 397493, 5576
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid