PKC delta Mouse anti-Human, Clone: 8E12, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA519701
Peptide Sequence: DILEKLFERE PTKRLGVTGN IKIHPFFKTI NWTLLEKRRL EPPFRPKVKS PRDYSNFDQE FLNEKARLSY SDKNLIDSMD QSAFAGFSFV NPKFEHLLEDProtein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed.
|PBS with no preservative; pH 7.4|
|Protein kinase C alpha type, PKC-A, PKC-alpha, PRKCA, PKCA, PRKACA, Protein kinase C beta type, PKC-B, PKC-beta, PKCB, PRKCB1, PRKCB, Protein kinase C gamma type, PKC-gamma, PKCG, PRKCG, Protein kinase C delta type, Tyrosine-protein kinase PRKCD, nPKC-delta, Sphingosine-dependent protein kinase-1, SDK1, PRKCD, Protein kinase C epsilon type, nPKC-epsilon, PRKCE, PKCE, Protein kinase C zeta type, nPKC-zeta, PRKCZ, PKC2, PKC zeta, Protein kinase C theta type, nPKC-theta, PRKCQ, PRKCT|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Immunocytochemistry, Immunofluorescence, Western Blot|
|PRKCD (NP_006245, 577 a.a. ∽ 676 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
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