PRMT5 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA141390
Suggested positive control: HeLa, NIH-3T3, Hela whole cell extract, antigen standard for PRMT5 (transient overexpression lysate).Protein arginine methylation is an important posttranslational modification in eukaryotic cells, which has been implicated in RNA processing and trafficking, receptor-mediated signaling, and transcription. PRMT5, also known as Janus kinase-binding protein 1 (JBP1) and Skb1Hs (human homolog of Skb1 of fission yeast can catalyze the formation of omega-N(G)-monomethylarginine and symmetric omega-N(G),N(G′)-dimethylarginine in a variety of proteins. Recombit PRMT5 can mono and dimethylate histone 2A and myelin basic protein. PRMT5 appears to have lower specific enzyme activity than PRMT1.
|PBS with 100μg/mL BSA and 0.02% sodium azide|
|HRMT1L5, IBP72, JBP1, SKB1, SKB1Hs|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Human PRMT5 amino acid sequence.|
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