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PRMT5 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA141390

Catalog No. 01-675-519


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Description

Description

Suggested positive control: HeLa, NIH-3T3, Hela whole cell extract, antigen standard for PRMT5 (transient overexpression lysate).

Protein arginine methylation is an important posttranslational modification in eukaryotic cells, which has been implicated in RNA processing and trafficking, receptor-mediated signaling, and transcription. PRMT5, also known as Janus kinase-binding protein 1 (JBP1) and Skb1Hs (human homolog of Skb1 of fission yeast can catalyze the formation of omega-N(G)-monomethylarginine and symmetric omega-N(G),N(G ft.)-dimethylarginine in a variety of proteins. Recombit PRMT5 can mono and dimethylate histone 2A and myelin basic protein. PRMT5 appears to have lower specific enzyme activity than PRMT1.
Specifications

Specifications

PRMT5
Polyclonal
PBS with 100μg/mL BSA and 0.02% sodium azide
O14744, Q8CIG8
HRMT1L5, IBP72, JBP1, SKB1, SKB1Hs
Rabbit
IgG
200 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
10419, 27374
Western Blot
Unconjugated
PRMT5
Liquid
PRMT5
Human PRMT5 amino acid sequence.
Protein G
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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