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PRMT5 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA511120

Catalog No. PIPA511120

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

This antibody is predicted to react with bovine, mouse, non-human primate and Xenopus based on sequence homology.

Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.
Specifications

Specifications

PRMT5
Polyclonal
PBS with 0.09% sodium azide
O14744
Protein arginine N-methyltransferase 5; EC 2.1.1.125; Shk1 kinase-binding protein 1 homolog; SKB1Hs; Jak-binding protein 1; 72 kDa ICln-binding protein; PRMT5; HRMT1L5; IBP72; JBP1; SKB1
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
10419
Western Blot
Unconjugated
PRMT5
Liquid
PRMT5
KLH conjugated synthetic peptide between 473-499 amino acids from the C-terminal region of human PRMT5
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
Antibody
Polyclonal
Human
Documents
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