Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

proBDNF Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA118374

Catalog No. 01-670-626

Add to cart



This antibody reacts with human, mouse and rat proBDNF and is also expected to recognise other mammalian proBDNF. No cross-reactivity with other proneurotrophins was detected in Western blot. Reconstitute with 20 µL of distilled water. After reconstitution keep aliquots at -20°C for a higher stability, and at 4°C with an appropriate antibacterial agent.

BDNF belongs to the neurotrophin family and regulates the survival and differentiation of neurons during development. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer′s, and Parkinson′s disease. BDNF promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. It is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.


Synthetic peptide corresponding to residues (C-E(69) L L D E D Q K V R P N E E(82) of human BDNF precursor.
Affinity chromatography
Human, Mouse, Rat
Immunohistochemistry (Frozen), Western Blot
1 mg/mL
Antibody with no preservative
P23560, P21237, P23363
Brain-derived neurotrophic factor, Abrineurin
20 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
12064, 24225, 627
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit