Progranulin Rat anti-Mouse, Clone: 333731, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA524063
In direct ELISAs and Western blots, 100% cross-reactivity with Recombinant human Progranulin is observed. Reconstitute at 0.5 mg/mL in sterile PBS.Progranulin is the precursor protein of Granulin also called as Proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature Granulin. Both Granulin and smaller cleavage product of Granulin regulates cell growth. Progranulin stimulates proliferation of many epithelial cells, promotes their anchorage-independent growth and, when overexpressed, confers epithelial tumorigenicity. Progranulin/epithelin gene is multifunctional, with important constitutive roles in epithelial homeostasis, reproductive, immunological, and neuronal function. Progranulin constitutively expressed in a number of epithelia, particularly in the skin, GI tract, and reproductive system. Progranulin is expressed in immune cells in vivo and in specific neurons in the brain.
|PBS with 5% trehalose and No Preservative|
|Granulin, PEPI, CLN11, GEP, GP88, PCDGF, PGRN, Acrogranin, Granulin-epithelin, PC Cell-derived growth factor, Proepithelin|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Frozen), Western Blot|
|Mouse myeloma cell line NS0-derived recombit mouse Progranulin/PGRN Thr18-Leu589|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok