PSCA Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA138516
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is breast, bladder or prostate adenocarcinoma.PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model.
|PBS with 1% BSA and 0.1% sodium azide; pH 7.6|
|PSCA, CDM, H-CAD, HCAD, L-CAD, LCAD, NAG22, caldesmon|
|-20° C, Avoid Freeze/Thaw Cycles|
|Synthetic peptide derived from extracellular region of human PSCA protein.|
|Antigen affinity chromatography|
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