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PSCA Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA138516

Catalog No. 01-673-882


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Description

Description

Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is breast, bladder or prostate adenocarcinoma.

PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model.
Specifications

Specifications

PSCA
Polyclonal
PBS with 1% BSA and 0.1% sodium azide; pH 7.6
O43653
PSCA, CDM, H-CAD, HCAD, L-CAD, LCAD, NAG22, caldesmon
Rabbit
IgG
1 mL
-20° C, Avoid Freeze/Thaw Cycles
Primary
8000
Immunohistochemistry (Paraffin)
Unconjugated
PSCA
Liquid
PSCA
Synthetic peptide derived from extracellular region of human PSCA protein.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
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