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PSMB3 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA528999

Catalog No. PIPA528999


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Description

Description

PA5-28999 targets Proteasome 20S beta 3 in WB applications and shows reactivity with Human samples. The PA5-28999 immunogen is recombit fragment corresponding to a region within amino acids 1 and 205 of Human Proteasome 20S beta 3. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Pseudogenes have been identified on chromosomes 2 and 12.
Specifications

Specifications

PSMB3
Polyclonal
Unconjugated
PSMB3
Liquid
PSMB3
Recombit fragment corresponding to a region within amino acids 1 and 205 of Human Proteasome 20S beta 3
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
0.96 mg/mL
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
P49720
HC10-II, proteasome chain 13, proteasome component C10-II, proteasome subunit beta type-3, proteasome theta chain
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
5691
Documents
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