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PSMD3 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527664

Catalog No. PIPA527664


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Description

Description

PA5-27664 targets Proteasome 26S S3 in IHC (P) and WB applications and shows reactivity with Human and mouse samples. The PA5-27664 immunogen is recombit fragment corresponding to a region within amino acids 1 and 240 of Human Proteasome 26S S3. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid.
Specifications

Specifications

PSMD3
Polyclonal
Unconjugated
PSMD3
Liquid
PSMD3
Recombit fragment corresponding to a region within amino acids 1 and 240 of Human Proteasome 26S S3
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
0.23 mg/mL
PBS with 10% glycerol and 0.01% thimerosal; pH 7
O43242, P14685
P58, RPN3, S3, TSTA2, 26S proteasome non-ATPase regulatory subunit 3, 26S proteasome regulatory subunit RPN3, 26S proteasome regulatory subunit S3, proteasome subunit p58, tissue specific transplantation antigen 2
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
22123, 5709
Documents
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