Acid Phosphatase 1 Sheep anti-Bovine, Human, Mouse, Rat, Polyclonal, Invitrogen™
Sheep Polyclonal Antibody
Manufacturer: Invitrogen PA112403
DescriptionLow molecular weight protein tyrosine phosphtases, including the human red cell phosphatase, HCPTP, are widely expressed cytosolic proteins of approximately 18kDa that exist in distinct isoforms and are highly selective for phosphotyrosine over phosphoserine or phosphotyrosine. The HCPTP-A and HCPTP-B proteins expressed in human red cells and placenta are fast and slow forms of red cell acid phosphatase5. Like other tyrosine phosphatases, HCPTP is sensitive to inhibition by vanadate, and has a catalytic mechanism that involves formation of a cystinylphosphate intermediate6. The crystal structure of the bovine heart derived enzyme BHPTP shows a four-stranded central parallel b sheet with flanking a helices and an active site cysteine residue in the typical tyrosine phosphatase sequence context, CXXXXXR.
|Acid Phosphatase 1|
|PBS with 0.08% sodium azide|
|P11064, P24666, Q9D358, P41498|
|HAAP, MGC111030, MGC3499|
|-20° C, Avoid Freeze/Thaw Cycles|
|11431, 24161, 280977, 52|
|Immunoprecipitation, Western Blot|
|Recombit human Protein Tyrosine Phosphatase expressed in E. coli.|
|Ammonium sulfate precipitation|
|Bovine, Human, Mouse, Rat|
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