PCDHA1 Mouse anti-Human, Clone: 3A3, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA522266
Peptide Sequence: DQAVYRVHLL ETTANGTLVT TLNASDADEG VNGEVVFSFD SGISRDIQEK FKVDSSSGEI RLIDKLDYEE TKSYEIQVKA VDKGSPPMSNThis gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
|PBS with no preservative; pH 7.4|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Western Blot|
|PCDHA1 (NP_061723, 243 a.a. ∽ 332 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok