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PCDHA9 Mouse anti-Human, Clone: 3C1, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA520826

Catalog No. PIMA520826


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Description

Description

Peptide Sequence: DVSPDIKSKF HMDPLSGAIT VIGHMDFEES RAHKIPVEAV DKGFPPLAGH CTLLVEVVDV NDNAPQLTIK TLSVPVKEDA QLGTVIALIS VIDLDADA

This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Specifications

Specifications

PCDHA9
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
Q9Y5H5
PCDHA9
PCDHA9 (NP_114063, 284 a.a. ∽ 381 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
ELISA, Western Blot
3C1
Unconjugated
PCDHA9
Liquid
Mouse
IgG1, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
9752
Documents
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