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PCDHB6 Mouse anti-Human, Clone: 2G11, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA522256

Catalog No. PIMA522256


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Description

Description

Peptide Sequence: ASLRVRDIND HAPEFPAREM LLKISEITMP GKIFPLKMAH DLDTGSNGLQ RYTISSNPHF HVLTRNRSEG RKFPELVLDK PLDREEQPQL RLTLIALDGG

This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3 ft. exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
Specifications

Specifications

PCDHB6
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
Q9Y5E3
POLR1E
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
56130
ELISA, Western Blot
2G11
Unconjugated
PCDHB6
Liquid
PCDHB6
PCDHB6 (NP_061762, 118 a.a. ∽ 217 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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