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PCDHGA10 Mouse anti-Human, Clone: 3A7, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA522247

Catalog No. PIMA522247


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Description

Description

Peptide Sequence: SDGGDPLRSG TVLVSVTVFD ANDNAPVFTL PEYRVSVPEN LPVGTQLLTV TATDRDEGAN GEVTYSFRKL PDTQLLKFQL NKYTGEIKIS ENLDYEET

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Specifications

Specifications

PCDHGA10
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
Q9Y5H3
PCDHGA10
PCDHGA10 (NP_061736.1, 219 a.a. ∽ 316 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
ELISA, Western Blot
3A7
Unconjugated
PCDHGA10
Liquid
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
56106
Documents
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