Cytohesin 1 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527793
PA5-27793 targets PSCD1 in WB applications and shows reactivity with Human samples. The PA5-27793 immunogen is recombit fragment corresponding to a region within amino acids 1 and 224 of Human PSCD1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. The encoded protein is 83% homologous to that of CYTH2.
|Recombit fragment corresponding to a region within amino acids 1 and 224 of Human PSCD1|
|Antigen affinity chromatography|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|B2-1, CYTOHESIN-1, D17S811E, PSCD1, SEC7, PH, SEC7 and coiled-coil domain-containing protein 1, SEC7 homolog B2-1, cytoadhesin 1, cytohesin-1, homolog of secretory protein SEC7, pleckstrin homology, Sec7 and coiled-coil domains 1|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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