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PSMB5 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA528086

Catalog No. PIPA528086


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Description

Description

PA5-28086 targets PSMB5 in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-28086 immunogen is synthetic peptide corresponding to a region within amino acids 199 and 263 of Human PSMB5. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

PSMB5
Polyclonal
Unconjugated
PSMB5
Liquid
PSMB5
Synthetic peptide corresponding to a region within amino acids 199 and 263 of Human PSMB5
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 20% glycerol and 0.01% thimerosal; pH 7
P28074
LMPX, MB1, X, PSX large multifunctional protease X, macropain epsilon chain, multicatalytic endopeptidase complex epsilon chain, proteasome beta 5 subunit, proteasome catalytic subunit 3, proteasome chain 6, proteasome epsilon chain, proteasome subunit MB1, proteasome subunit
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
5693
Documents
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