PSMD7 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527941
PA5-27941 targets PSMD7 in IF and WB applications and shows reactivity with Human samples. The PA5-27941 immunogen is recombit fragment corresponding to a region within amino acids 47 and 324 of Human PSMD7. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.
|Recombit fragment corresponding to a region within amino acids 47 and 324 of Human PSMD7|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7|
|MOV34, P40, Rpn8, S12, 26S proteasome non-ATPase regulatory subunit 7, 26S proteasome regulatory subunit S12, 26S proteasome regulatory subunit rpn8, Moloney leukemia virus-34 proviral integration, Mov34 homolog, proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homo|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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