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PSMD8, Polyclonal, Invitrogen™
Description
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.
Specifications
Specifications
| Antigen | PSMD8 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 1mg/mL |
| Conjugate | Unconjugated |
| Gene | PSMD8 |
| Gene Accession No. | P48556, Q9CX56 |
| Gene Alias | HIP6, HYPF, MGC1660, Nin1p, Rpn12, S14, p31 |
| Gene Symbols | PSMD8 |
| Host Species | Chicken |
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