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PSMF1, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA131806

Catalog No. PIPA131806

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.

PA1-31806 detects PSMF1 from human samples.PA1-31806 has been successfully used in Western blot applications.The PA1-31806 immunogen is: Peptide with sequence DHLPPPGYDDMYL, from C Terminus of the protein sequence according to NP_006805; NP_848693.
Specifications

Specifications

PSMF1
Polyclonal
Unconjugated
PSMF1
Purified
PSMF1
Peptide with sequence DHLPPPGYDDMYL, from C Terminus of the protein sequence according to NP_006805; NP_848693.
IgG fraction
RUO
Antibody
Polyclonal
Human, Murine, Rat
Western Blot
0.5mg/mL
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Q92530, Q8BHL8, Q5XIU5
RP4-545L17.1, PI31
Goat
IgG
50μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
9491
Documents
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