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JMJD6, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523305

Catalog No. PIPA523305

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

PTDSR, also known as jumonji domain containing 6, is a 403 amino acid containing nuclear protein belonging to the PTDSR family with a JmjC domain. Like other JmjC domain-containing proteins PTDSR is predicted to function as protein hydroxylases or histone demethylases. PTDSR is an arginine demethylase which demethylates histone H3 at 'Arg-3' and histone H4 at 'Arg-4' and is known to function in the differentiation of multiple organs during embryogenesis, and regulate hematopoietic differentiation and macrophage cytokine responses. First identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells, PTDSR was later indicated not to directly function in the clearance of apoptotic cells. It is ubiquitously expressed in most of the tissues and upregulated in patients with chronic pancreatitis and upon cytokine treatment, but not upon TNF-alpha treatment.

Specifications

Specifications

PTDSR
Polyclonal
Unconjugated
JMJD6
Purified
JMJD6, LOC100058567
Synthetic peptide (127 DSPLYIFDSSYGEHPKRR 144) of PTDSR protein.
Antigen affinity chromatography
Store at 4°C short term. For long term storage, Store at -20°C, avoiding freeze/thaw cycles.
Primary
23210
Western Blot
0.5mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Q58DS6, Q6NYC1, Q9ERI5
PSR, PTDSR, PTDSR1, bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, histone arginine demethylase JMJD6, jmjC domain-containing protein 6, jumonji domain-containing protein 6, lysyl-hydroxylase JMJD6, peptide-lysine 5-dioxygenase JMJD6, phosphatidylserine receptor
Rabbit
IgG
100μg
Antibody
Polyclonal
Bovine, Canine, Equine, Human, Marsupial, Murine, Non-human Primate
Documents
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