PUF60 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527605
PA5-27605 targets PUF60 in WB applications and shows reactivity with Human samples. The PA5-27605 immunogen is recombit protein fragment corresponding to a region within amino acids 1 and 258 of Human PUF60. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.
|Recombit protein fragment corresponding to a region within amino acids 1 and 258 of Human PUF60|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7|
|FIR, RoBPI, SIAHBP1, 60 kDa poly(U)-binding-splicing factor, FBP interacting repressor, FBP-interacting repressor, Ro ribonucleoprotein binding protein 1, Ro ribonucleoprotein-binding protein 1, fuse-binding protein-interacting repressor, poly(U)-binding-splicing factor PUF60, poly-|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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