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PYY Rabbit anti-Human, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA136142

Catalog No. 01-672-298


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Description

Description

A suggested positive control for IHC is rat colon tissue. An overnight incubation at 4°C is recommended. Reconstitute with 50-100 µL of distilled water, and dilute further in 0.1M PBS with 1% BSA and 0.1% sodium azide.

Peptide tyrosine-tyrosine amide, or PYY, is a major metabolite of the gut hormone PYY and is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation. PYY is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thus disinhibiting anorexigenic POMC neurons. The anorexigenic effect of PYY is additive to that of the co-secreted gut hormone GLP-1.
Specifications

Specifications

PYY
Polyclonal
whole serum with 0.1% sodium azide
P10082, P10631
PYY1
Rabbit
IgG
RUO
Antibody
Polyclonal
Human, Rat
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Unconjugated
PYY
Lyophilized
PYY
Synthetic porcine Peptide YY.
50 μL
4° C
Primary
287730, 5697
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