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R-Cadherin Mouse, Unlabeled, Clone: 48, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 610414

Catalog No. BDB610414

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R-Cadherin was first isolated from chicken retina, but was subsequently shown to be present and highly conserved in a variety of tissues from several different species. A 913 amino acid polypeptide, R-Cadherin is highly homologous to Cadherin-4, but is most closely related to another family member, N-Cadherin. In experiments using chimeric L cells expressing chicken or mouse Cadherins, those cells expressing mouse or chicken R-Cadherin were able to aggregate with each other as well as with cells expressing N-Cadherin. However, there was no aggregation of R-Cadherin expressing cells, with P- or E-Cadherin expressing cells. This suggests that the roles of specific cadherins are conserved among types in the determination of heterogenous cell segregation and distribution during tissue morphogenesis and maintenance.



Affinity Purified
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Cell Biology
Murine, Rat
Western Blot
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
IgG2a, κ
Store undiluted at -20°C.
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