RAB3c Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA1772

Catalog No. PA1772

Description

PA1-772 detects rab 3C from mouse and rat tissues and cells. PA1-772 has been successfully used in Western blot and immunoprecipitation procedures. By Western blot, this antibody detects a 22 kDa protein representing rab 3C from AtT20 cell extract. PA1-772 immunogen is a synthetic peptide corresponding to residues M(9) A S A Q D A R F G Q K D S S D Q N(26) C of rat RAB3C. This immunizing peptide (Cat. No. PEP-106) is available for use in neutralization and control experiments.

Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 Rab proteins that have been described in mammals. Rab 3C is found in brain, adrenal gland, and pituitary.

Specifications

• Antigen: RAB3C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: Q96E17, P62823, P62824
• Gene Symbols: RAB3C
• Immunogen: Synthetic peptide corresponding to residues M(9) A S A Q D A R F G Q K D S S D Q N(26) C of rat RAB3C.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunoprecipitation, Western Blot
• Concentration: 1 mg/mL
• Gene: RAB3C
• Gene Alias: Ras-Associated Protein 3C
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 115827, 171058, 67295
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid