RAC2 Goat anti-Human, Polyclonal, Invitrogen™
Goat Polyclonal Antibody
Manufacturer: Invitrogen PA19091
This antibody is predicted to react with mouse and rat based on sequence homology.RAC, a small GTPase in the ras family, regulates the formation of membrane ruffles, lamellipodia and filopodia. It is involved in cytoskeletal actin organization and transformation. The p21 activated kinases (PAKs) are direct targets of active Rac and Cdc42 which can induce the assembly of polarized cytoskeletal structures when expressed in fibroblasts. RAC1 and RAC2 are also essential components of NADPH oxidase, the enzyme responsible for generating free radicals.
|Synthetic peptide corresponding to the C terminus amino acids PQPTRQQKRACSLL.|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3|
|RAC2; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2); EN-7; Ras-related C3 botulinum toxin substrate 2; rho f|
|-20° C, Avoid Freeze/Thaw Cycles|
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