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RAD21 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA528344

Catalog No. PIPA528344


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Description

Description

PA5-28344 targets RAD21 in IHC (P), IF, and WB applications and shows reactivity with Human and mouse samples. The PA5-28344 immunogen is recombit fragment corresponding to a region within amino acids 6 and 399 of Human RAD21. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.
Specifications

Specifications

RAD21
Polyclonal
Unconjugated
RAD21
Liquid
RAD21
Recombit fragment corresponding to a region within amino acids 6 and 399 of Human RAD21
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.44 mg/mL
PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7
O60216, Q61550
HR21, HRAD21, MCD1, NXP1, SCC1, hHR21, NXP-1, SCC1 homolog, double-strand-break repair protein rad21 homolog, nuclear matrix protein 1, protein involved in DNA double-strand break repair
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
19357, 5885
Documents
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