RAD21 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA528344
PA5-28344 targets RAD21 in IHC (P), IF, and WB applications and shows reactivity with Human and mouse samples. The PA5-28344 immunogen is recombit fragment corresponding to a region within amino acids 6 and 399 of Human RAD21. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.
|Recombit fragment corresponding to a region within amino acids 6 and 399 of Human RAD21|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7|
|HR21, HRAD21, MCD1, NXP1, SCC1, hHR21, NXP-1, SCC1 homolog, double-strand-break repair protein rad21 homolog, nuclear matrix protein 1, protein involved in DNA double-strand break repair|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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